Engineering work is taking place between Didcot Parkway and Tackley, closing all lines late on Saturday night.
After 22:45, buses will replace trains between Didcot Parkway and Oxford.
Check before you travel:
You can plan your journey using the National Rail Journey Planner.
Replacement bus travel advice:
For helpful advice if you need to travel on a rail replacement service, including accessibility and bicycle information, please use our Rail Replacement Services page.
You can find the pick-up and drop-off location of rail replacement services by checking station signage or by searching for your station on our Find a Station page.
Please be advised that replacement vehicles may be busier than usual, and you should allow extra time for your journey.